Learn More About Cross-Linking

Learn about one of the treatment options available to treat this rare disease.

Top Questions to Ask Your Eye Doctor Download PDF

Avedro's FDA Approved Cross-linking

Avedro’s cross-linking procedure is FDA-approved, clinically proven, safe and effective.

Ask Your Doctor if she/he is Performing FDA Approved Cross-Linking

Photrexa Viscous (riboflavin 5′-phosphate in 20% dextran ophthalmic solution) & Photrexa (riboflavin 5′-phosphate ophthalmic solution) are:

  • The only FDA-approved riboflavin ophthalmic solution drugs
  • Supported with published, FDA reviewed, clinical data
  • Manufactured in a world-class FDA registered facility
  • Manufactured in compliance with FDA guidelines
  • Highest quality, controlled manufacturing process

Don’t be afraid to ask your doctor what device he/she uses for cross-linking and whether or not the procedure is FDA-approved or investigational.


Learn more about this outpatient procedure

View our Living with Keratoconus Patient Brochure.

Patient FAQs

Discover answers to the most common questions surrounding cross-linking

Visit the Patient FAQ Section to learn more.

It is estimated that...

1 Out of Every 2,000

persons in the general population have Keratoconus1

You can find more information from the National Keratoconus Foundation.

1. Kennedy R. H., Bourne W. M., Dyer J. A. A 48-year clinical and epidemiologic study of keratoconus. The American Journal of Ophthalmology. 1986;101(3):267–273. doi: 10.1016/0002-9394(86)90817-2.

Keratoconus, when left untreated, can result in significant deterioration of vision, and may lead to multiple corneal transplants, with the potential to adversely affect patients’ quality of life."

Rajesh Rajpal, MD, Chief Medical Officer for Avedro

What are Patients Saying? View Stories

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5 hours ago

Living with KC

#FactFriday - 4.2 million Americans ages 40 and older are visually impaired. #LowVisionAwarenessMonth nei.nih.gov/nehep/lvam ... See MoreSee Less

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8 hours ago

Living with KC

Still confused about which #crosslinking procedures are FDA approved? Read our blog to clear up and confusion! www.livingwithkeratoconus.com/blog/what-to-know-about-fda-approved-treatments/ ... See MoreSee Less

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1 week ago

Living with KC

Did you know that if you donate your cornea, you could be able to restore sight to 2 people? This #NationalDonorDay we want to say thanks to all the registered donors! www.donatelife.net/statistics/ ... See MoreSee Less

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#FactFriday - 4.2 million Americans ages 40 and older are visually impaired. #LowVisionAwarenessMonth https://t.co/NNoEoeczxi

Still confused about which #crosslinking procedures are FDA approved? Read our blog to clear up and confusion! https://t.co/CG73OTR3R2

Do you know if your insurance covers #crosslinking? Visit our website to find out: https://t.co/B5stNJdheA

Did you know that people living with low #vision are still able to maintain their independence & quality of life? Watch this video from the @NatEyeInstitute Health Education Program to hear stories of hope & independence! #LowVisionAwarenessMonth https://t.co/7tWFN0GxZd

"I didn't know how I would be able to do anything without my vision...it crushed me." - Aaron following his #keratoconus diagnosis. https://t.co/4PKt7bwQEo

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