Patient Perspective on Cross-Linking

Learn more about the importance of early diagnosis and treatment from a keratoconus patient and her treating physician.

A General Overview

Corneal cross-linking is a minimally invasive outpatient procedure that combines the use of Photrexa® Viscous (riboflavin 5’-phosphate in 20% dextran ophthalmic solution), Photrexa® (riboflavin 5’-phosphate ophthalmic solution) and the KXL® system for the treatment of progressive keratoconus.

Corneal Cross-Linking:
  • Creates new corneal collagen cross-links
  • Results in a shortening and thickening of the collagen fibrils
  • Leads to the stiffening of the cornea

Top Questions to Ask Your Eye Doctor Download PDF

FDA Approval

The first and only therapeutic products for corneal cross-linking which have been FDA approved to treat progressive keratoconus.

In April 2016, the FDA approved Photrexa® Viscous (riboflavin 5’-phosphate in 20% dextran ophthalmic solution) and Photrexa® (riboflavin 5’-phosphate ophthalmic solution) and the KXL® System for corneal cross-linking, a minimally invasive outpatient procedure that combines the use of Vitamin B2 eye drops and ultra-violet (UV) light.

The approval of Photrexa Viscous, Photrexa and the KXL System offers an effective treatment for patients who, until recently, had no therapeutic options to limit the progression of this sight-threatening disease.

Cross-Linking

Learn more about this outpatient procedure

View our Living with Keratoconus Patient Brochure.

Patient FAQs

Discover answers to the most common questions surrounding cross-linking

Visit the Patient FAQ Section to learn more.

It is estimated that...

1 Out of Every 2,000

persons in the general population have Keratoconus1

You can find more information from the National Keratoconus Foundation.

1. Kennedy R. H., Bourne W. M., Dyer J. A. A 48-year clinical and epidemiologic study of keratoconus. The American Journal of Ophthalmology. 1986;101(3):267–273. doi: 10.1016/0002-9394(86)90817-2.

Corneal cross-linking provides patients a much-needed option to treat this debilitating disease. Patients suffering from progressive keratoconus can now receive a therapeutic treatment that has been rigorously tested and approved."

Mary Prudden, Executive Director for the National Keratoconus Foundation

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2 weeks ago

Living with KC

A routine visit to the #eye doctor changed 16 year old Max's life forever. Since learning he was #LivingWithKC, he was determined to not let his diagnosis control his future. Visit our website to read Max's #KCJourney! ow.ly/bZIY30lv3kc ... See MoreSee Less

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If you're #LivingWithKC and using #contacts, proper maintenance is important to keep and maintain healthy #vision.

The National Keratoconus Foundation shares some tips from the @CDCgov on how to take care of your lenses! https://t.co/DUFFUsWmk5

Want more information on #keratoconus and treatment options? Catch up on our #KCExpert posts today! https://t.co/BP7yMx7yEJ

We want to hear from you! Message us if you've undergone #crosslinking and had a positive experience with insurance coverage! https://t.co/XrYcyAfYho

Curious about #crosslinking? In our latest blog, #KCExperts Dr. Parker of @ParkerCornea and Dr. Iuorno of @CommonwealthECA share their expertise on the FDA-approved treatment and what to expect during the procedure https://t.co/PETJinncJn

A routine visit to the #eye doctor changed 16 year old Max's life forever. Since learning he was #LivingWithKC, he was determined to not let his diagnosis control his future. Visit our website to read Max's #KCJourney! https://t.co/kqlYH4TZ5J

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