Patient Perspective on Cross-Linking

Learn more about the importance of early diagnosis and treatment from a keratoconus patient and her treating physician.

A General Overview

Corneal cross-linking is a minimally invasive outpatient procedure that combines the use of Photrexa® Viscous (riboflavin 5’-phosphate in 20% dextran ophthalmic solution), Photrexa® (riboflavin 5’-phosphate ophthalmic solution) and the KXL® system for the treatment of progressive keratoconus.

Corneal Cross-Linking: A New Standard of Care for Progressive Keratoconus

Corneal collagen cross-linking is an innovative therapy that has transformed the treatment of progressive keratoconus. Historically, as many as 1 in 5 patients with progressive keratoconus have required a corneal transplant, with more than half needing multiple transplants within 20 years.1, 2

¹Pramanik S, Musch DC, Sutphin JE, Farjo AA. Extended long-term outcomes of penetrating keratoplasty for keratoconus. Ophthalmology 2006;113(9):1633-8.
2Maharana PK, Agarwal K, Jhanji V, Vajpayee RB. Deep anterior lamellar keratoplasty for keratoconus: a review. Eye Contact Lens 2014;40(6):382-9.

Top Questions to Ask Your Eye Doctor Download PDF

FDA Approval

The first and only therapeutic products for corneal cross-linking which have been FDA approved to treat progressive keratoconus.

In April 2016, the FDA approved Photrexa® Viscous (riboflavin 5’-phosphate in 20% dextran ophthalmic solution) and Photrexa® (riboflavin 5’-phosphate ophthalmic solution) and the KXL® System for corneal cross-linking, a minimally invasive outpatient procedure that combines the use of Vitamin B2 eye drops and ultra-violet (UV) light.

The approval of Photrexa Viscous, Photrexa and the KXL System offers an effective treatment for patients who, until recently, had no therapeutic options to limit the progression of this sight-threatening disease.

Don’t wait to call the eye doctor if you notice changes in your child’s vision! Ask about FDA approved cross-linking, clinically proven to limit the progression of this sight-threatening disease.

Cross-Linking

Learn more about this outpatient procedure

View our Living with Keratoconus Patient Brochure.

Patient FAQs

Discover answers to the most common questions surrounding cross-linking

Visit the Patient FAQ Section to learn more.

It is estimated that...

1 Out of Every 2,000

persons in the general population have Keratoconus1

You can find more information from the National Keratoconus Foundation.

1. Kennedy R. H., Bourne W. M., Dyer J. A. A 48-year clinical and epidemiologic study of keratoconus. The American Journal of Ophthalmology. 1986;101(3):267–273. doi: 10.1016/0002-9394(86)90817-2.

Corneal cross-linking provides patients a much-needed option to treat this debilitating disease. Patients suffering from progressive keratoconus can now receive a therapeutic treatment that has been rigorously tested and approved."

Mary Prudden, Executive Director for the National Keratoconus Foundation

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Prevent Blindness recognizes September as Sports Eye Safety Awareness Month! Did you know that 90% of all sports-related eye injuries can be prevented by wearing proper #eye protection? ow.ly/HmaB50w4Fie ... See MoreSee Less

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FDA approved #crosslinking is now widely covered by insurance! Visit our website to see if your insurance company is covering the procedure. ow.ly/eOM250vLwvq ... See MoreSee Less

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Curious about the #crosslinking recovery process? To help others, Bekah created a video journal highlighting her journey before receiving the procedure to 10 days post-CXL. Watch it now! https://t.co/fjhg7Jc08G

Itchy #eyes can be annoying! @Healthline shares some home remedies to help with this uncomfortable issue. https://t.co/E3gzkL8hDB

Prevent Blindness (@PBA_savingsight) recognizes September as Sports Eye Safety Awareness Month! Did you know that 90% of all sports-related eye injuries can be prevented by wearing proper #eye protection? https://t.co/7zky18KmDT

FDA approved #crosslinking is now widely covered by insurance! Visit our website to see if your insurance company is covering the procedure. https://t.co/Td8lB14lmp

Did you know that mixing up your eye drop medications with other medicine is actually very common? To help avoid any mishaps, @aao_ophth shares six tips to prevent this mistake: https://t.co/5vnSdvvs3y

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